At Cape Fear Physical Medicine and Rehab, we are dedicated to providing comprehensive solutions for weight management as part of our holistic approach to physical medicine and rehabilitation. Ozempic and Zepbound are two injectable medications that our medical team may consider as part of a personalized weight management plan. These medications are designed to support weight loss in individuals with obesity or who are overweight, particularly when lifestyle changes alone have not been sufficient.

• Ozempic (semaglutide) is a GLP-1 receptor agonist, initially used for type 2 diabetes but also effective for weight loss. Clinical studies show that patients may lose 5–10% of their body weight over about 16 months, with higher-dose options (such as Wegovy) demonstrating even greater results.

• Zepbound (tirzepatide) is a newer medication that acts on both GLP-1 and GIP receptors. Recent research has shown that Zepbound can result in an average weight loss of up to 20% over approximately 18 months, making it a highly effective option for chronic weight management.

Selecting the right medication is a personalized process. At Cape Fear Physical Medicine and Rehab, our providers thoroughly evaluate each patient’s medical history, current health, and rehabilitation objectives before recommending any medication. We monitor the effectiveness, side effects, and potential interactions with other treatments to ensure that medications like Ozempic or Zepbound are safely and effectively incorporated into your care plan.

At Cape Fear Physical Medicine and Rehab, we recognize the importance of weight management for overall health, rehabilitation, and quality of life, particularly for those with chronic pain, mobility issues, or metabolic conditions. We provide guidance on modern weight management options, including injectable treatments like Ozempic (semaglutide) and Zepbound (tirzepatide).

Zepbound tends to offer faster weight loss results compared to Ozempic, based on clinical trials. It has shown higher average weight loss percentages, with some patients losing up to 20% of their body weight at higher doses over a longer period. This is due to Zepbound’s dual-hormone mechanism, which targets both fat reduction and appetite regulation.

Ozempic, while effective, typically results in more moderate weight loss. It is still a powerful option, especially for those with type 2 diabetes, but it generally produces slower weight loss compared to Zepbound. The speed of weight loss for both medications can vary depending on the individual, their lifestyle, and how their body responds to the treatment.

For our patients at Cape Fear Physical Medicine and Rehab, effective weight management can greatly enhance rehabilitation outcomes, reduce strain on joints, and improve mobility and pain levels. If you’re interested in exploring Ozempic or Zepbound as part of your weight management and rehabilitation plan, our clinical team will carefully evaluate your medical history, current conditions, and goals to determine the safest and most effective option for you. We’re here to support your journey to better health—every step of the way.

When considering weight loss medications, it’s important to choose the right option based on your specific health needs, lifestyle, and weight loss goals. Both Ozempic and Zepbound are effective treatments, but they work differently and may be more suitable for different individuals. Below is an overview of who should consider using each medication based on their unique circumstances.

Ozempic:

• Individuals with type 2 diabetes are looking for weight loss support alongside blood sugar control.

• People who prefer a once-weekly injection for convenience.

• Those who have struggled with appetite control and need medication to help reduce hunger.

• Suitable for individuals with a history of cardiovascular disease, as Ozempic may also provide heart health benefits.

Zepbound:

• Individuals looking for a medication that may offer a multi-faceted approach to weight loss.

• People who prefer a daily medication regimen and are open to adjusting the dose as per their healthcare provider’s recommendation.

• Those who have not responded well to other weight loss medications or lifestyle changes alone.

• Suitable for individuals seeking comprehensive weight management strategies that target both fat reduction and appetite regulation.

Most importantly, any decision regarding weight loss medications is made together with you, your provider, and our care team at Cape Fear Physical Medicine and Rehab. We conduct thorough medical evaluations to ensure the safest and most effective treatment options—especially since certain conditions, such as a history of medullary thyroid cancer, may mean these medications are not suitable. We are committed to helping you achieve your health and wellness goals through personalized, evidence-based care.

At Cape Fear Physical Medicine and Rehab, our team is committed to supporting patients on their weight management journeys with the latest, evidence-based treatments. Two effective injectable medications we may prescribe are Ozempic and Zepbound.

Ozempic is typically administered once a week via an injection. This weekly dosage is designed to provide consistent weight loss results by helping to reduce appetite and regulate blood sugar levels. Many patients begin to notice changes within the first few weeks, with continued improvement as they maintain their weekly injections. Ozempic’s once-weekly schedule offers convenience for individuals seeking a manageable routine for weight loss.

Zepbound, in contrast, may be taken more frequently, typically daily or as directed by a healthcare provider. The frequency of Zepbound can vary depending on the individual’s treatment plan and response to the medication. Both medications aim to support weight loss, but their dosing schedules differ, with Zepbound generally requiring more frequent administration compared to Ozempic’s once-weekly injection.

At Cape Fear Physical Medicine and Rehab, we provide personalized guidance on how and when to administer these medications, ensuring you have the support and education needed for safe and effective use. If you ever miss a dose, our team will advise you on the best course of action based on your individual circumstances and the medication guide. We are here to partner with you every step of the way toward better health and well-being.

Dr. Meisha K. Abbasinejad, a board-certified specialist in obesity medicine at Cape Fear Physical Medicine, is dedicated to helping patients find the right weight loss solutions based on their individual needs. Ozempic, a GLP-1 medication, has been shown to effectively reduce appetite and help with weight loss by mimicking a natural hormone in the body. It’s an excellent option for individuals looking to manage their weight while improving other aspects of their health, such as blood sugar control.

On the other hand, Zepbound is another promising treatment, offering a multi-faceted approach to weight loss. As a board-certified expert in obesity medicine, Dr. Abbasinejad works closely with her patients to assess their overall health and weight loss goals, guiding them in selecting the most suitable option. Whether Ozempic or Zepbound is the better choice depends on factors like your medical history, lifestyle, and how your body responds to treatment. Dr. Abbasinejad ensures that each patient receives personalized care and the support needed to achieve their weight loss objectives effectively and safely.

Contact us today for more information, or simply schedule an appointment online. We are conveniently located at 1540 Purdue Dr, Ste. 200, in Fayetteville, NC 28303. We serve patients from Fayetteville NC, Woodfield NC, Hope Mills NC, Fort Bragg NC, Eastover NC, and surrounding areas.