Zepbound vs Ozempic: Effectiveness in Weight Loss Treatment
Dr. Meisha K. Abbasinejad, MD, board-certified in Obesity Medicine, evaluates Zepbound and Ozempic based on each patient’s unique needs. Zepbound may offer greater weight loss with its dual-action mechanism, while Ozempic effectively reduces appetite. She tailors the treatment to ensure the best results for each patient. Contact us today or book an appointment online. We are conveniently located at 1540 Purdue Dr, Ste. 200, in Fayetteville, NC 28303.


Table of Contents:
What is the difference between Zepbound and Ozempic for weight loss?
How do Zepbound and Ozempic work for weight loss?
How are Zepbound and Ozempic administered for weight loss?
How often do I need to inject Zepbound or Ozempic for weight loss?
How Does Dr. Meisha K. Abbasinejad, MD, Evaluate the Benefits of Zepbound vs. Ozempic for Weight Management?
At Cape Fear Physical Medicine and Rehab, we understand that weight management is a critical part of overall health and well-being. For individuals struggling with weight loss, two prescription medications that are often discussed are Zepbound and Ozempic. Both medications are injectables designed to support weight loss efforts, but their mechanisms and effectiveness vary, which is why it’s important to work with our providers to determine the best approach tailored to your unique needs.
Zepbound (Tirzepatide):
Zepbound is a newer medication approved specifically for weight management in adults who are overweight or obese. It works by activating two hormone receptors—GLP-1 and GIP—helping to regulate appetite, increase feelings of fullness, and decrease food intake. This dual-action mechanism supports more significant weight loss compared to other treatments, making it an excellent option for those struggling to manage their weight.
Ozempic:
Ozempic, while primarily approved for managing type 2 diabetes, is often prescribed off-label for weight loss. It works by activating the GLP-1 receptor, which reduces appetite and promotes satiety. For weight management, a higher-dose version, Wegovy, has been FDA-approved. Like Zepbound, Ozempic is administered as a weekly injection.
Choosing the Right Medication:
At Cape Fear Physical Medicine and Rehab, our experienced team, led by Dr. Meisha K. Abbasinejad, MD, board-certified in Obesity Medicine, will work with you to determine which medication is best suited for your weight loss goals. Zepbound may offer greater weight loss benefits for some individuals, but both medications have similar side effects, such as nausea and gastrointestinal discomfort. Together, we’ll ensure a safe and effective weight loss journey by taking a comprehensive approach that combines medication with lifestyle changes like proper nutrition and physical activity.
If you’re interested in learning more about how Zepbound and Ozempic can fit into your personalized weight loss plan, schedule a consultation with us today. Our goal is to support you in achieving sustainable weight loss and improving your overall health.
At Cape Fear Physical Medicine and Rehab, we understand that achieving and maintaining a healthy weight is crucial for your overall well-being and quality of life. Weight loss can have a significant impact on mobility, reduce pain, and improve overall health, especially for those with chronic conditions.
Zepbound and Ozempic are two medications that have gained attention for their effectiveness in supporting weight loss. Though originally developed for type 2 diabetes management, both have shown promising results in helping individuals manage their weight.
Ozempic contains a GLP-1 receptor agonist that mimics the action of a hormone in your body. It helps regulate blood sugar, slows stomach emptying, and promotes a feeling of fullness, which leads to reduced appetite and calorie intake. This can help support safe and sustained weight loss.
Zepbound, on the other hand, features tirzepatide, which uniquely activates both GLP-1 and GIP receptors. By targeting both receptors, Zepbound may offer enhanced appetite suppression and increased satiety, leading to potentially greater weight loss results for some individuals.
For patients at Cape Fear Physical Medicine and Rehab, these medications are used as part of a comprehensive weight management plan. Weight loss improves metabolic health, reduces stress on joints, and can enhance participation in rehabilitation and physical therapy.
Consulting with a healthcare provider is essential to determine if Ozempic or Zepbound is right for your needs. Dr. Meisha K. Abbasinejad, MD, board-certified in Obesity Medicine, and our team are here to guide you through the process, monitor your progress, and ensure a safe and effective approach to weight management.
At Cape Fear Physical Medicine and Rehab, we understand that weight management is a key component of overall health, especially for individuals facing obesity or weight-related medical conditions. As part of our comprehensive approach to physical medicine and rehabilitation, we offer guidance and support for patients who may benefit from advanced medical therapies such as Zepbound (tirzepatide) and Ozempic.
Both Zepbound and Ozempic are injectable medications that have shown effectiveness in supporting weight loss when combined with lifestyle changes. These medications are administered once weekly via a subcutaneous injection—meaning the medication is injected just under the skin, typically in the abdomen, thigh, or upper arm. At Cape Fear Physical Medicine and Rehab, our experienced healthcare professionals will teach you or your caregiver how to safely and comfortably prepare and administer these injections using pre-filled pen devices. We also emphasize the importance of rotating injection sites to minimize the risk of irritation or other local side effects.
During your visits, we will work closely with you to determine the most appropriate starting dose, gradually increasing it over time as needed to minimize gastrointestinal side effects and ensure your body adjusts well to the medication. Our team will provide clear, personalized instructions and ongoing support to help you achieve the best results.
Before initiating therapy with Zepbound or Ozempic, our providers will thoroughly review your medical history, current medications, and any other health concerns to ensure these treatments are safe and suitable for you. We are here to answer your questions, address any side effects, and help you troubleshoot issues—such as what to do if a dose is missed.
At Cape Fear Physical Medicine and Rehab, our goal is to help you reach and maintain a healthy weight as part of your overall rehabilitation and wellness journey. If you are interested in learning more about weight loss medications or wish to discuss your options, please contact our office to schedule a consultation.
At Cape Fear Physical Medicine and Rehab, we are committed to supporting your weight loss journey and overall health. Two commonly prescribed medications for weight management are Zepbound (tirzepatide) and Ozempic. Both of these injectable medications are effective tools in aiding weight loss and managing type 2 diabetes.
How to Take Your Medication:
Both Zepbound and Ozempic are administered via a subcutaneous (under the skin) injection once a week. For optimal results, it’s important to choose a consistent day each week for your injection. This ensures that the medication remains at steady levels in your body, enhancing its effectiveness and minimizing the chance of missing a dose.
What if You Miss a Dose?
If you miss your weekly injection, take it as soon as you remember—provided it’s within five days of your missed dose. If more than five days have passed, skip the missed dose and continue with your next scheduled injection. It is important not to double your dose within the same week to make up for the missed one.
Your Individualized Plan:
At Cape Fear Physical Medicine and Rehab, Dr. Meisha K. Abbasinejad, MD, board-certified in Obesity Medicine, and our team will work with you to determine the right medication and dosing schedule based on your individual health needs. Please refrain from adjusting your medication or schedule without first consulting your healthcare provider. If you have any questions or concerns regarding your injections or dosage, our team is here to offer support and guidance throughout your treatment.
If you’re interested in learning more about Zepbound, Ozempic, and how they can help with your weight loss goals, schedule a consultation with Cape Fear Physical Medicine and Rehab today. We’re here to assist you every step of the way.
Dr. Meisha K. Abbasinejad, MD, board-certified in Obesity Medicine, evaluates the benefits of Zepbound (tirzepatide) vs. Ozempic by considering each patient’s unique needs and weight loss goals. She looks at factors like overall health, lifestyle, and previous weight loss attempts.
Zepbound, which activates both GLP-1 and GIP receptors, may offer enhanced appetite control and greater weight loss benefits for some individuals. Ozempic, which targets the GLP-1 receptor, can also support significant weight loss by reducing appetite and increasing satiety. Dr. Abbasinejad uses her expertise to tailor treatment plans and ensure patients achieve their weight management goals safely and effectively.
Dr. Abbasinejad is committed to helping patients achieve their weight loss goals with personalized care. By evaluating the benefits of Zepbound and Ozempic, she ensures the best treatment for each individual. Contact us today or book an appointment online. We are conveniently located at 1540 Purdue Dr, Ste. 200, in Fayetteville, NC 28303. We serve patients from Fayetteville NC, Woodfield NC, Hope Mills NC, Fort Bragg NC, Eastover NC, and surrounding areas.

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Additional Services You May Like
▸ Weight Loss & Wellness Program
▸ Botox for Migraine
▸ EMG Nerve Conduction Studies
▸ Epidural Steroid Injections
▸ Radiofrequency Ablation
▸ Rehabilitation Consultations
▸ Facet Injections
▸ Sacroiliac Joint Injections
▸ Joint Injections
▸ Genicular Nerve Blocks
▸ Prosthetic Evaluation/Management
▸ Adjuvant Therapy/Care
▸ Spasticity Management
▸ Stroke Treatment
▸ Multiple Sclerosis
▸ Spinal Cord Injury
▸ Traumatic Brain Injury
▸ Lifestyle Medicine
▸ Phentermine
▸ Qsymia
▸ Contrave






