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Semaglutide vs Ozempic vs Wegovy vs Mounjaro: What’s the Difference?

Semaglutide vs Ozempic vs Wegovy vs Mounjaro: What’s the Difference?

Semaglutide, Ozempic, and Wegovy are all GLP-1 receptor agonists, signaling proteins that have been approved by the FDA as effective treatments for type 2 diabetes and/or obesity. These medications, often recommended by professionals like those at Cape Fear Physical Medicine in Fayetteville, NC, share a common mechanism of action. For more information, contact us today or schedule an appointment online. We are conveniently located at 1540 Purdue Dr, Ste. 200, in Fayetteville, NC 28303.

Semaglutide vs Ozempic vs Wegovy vs Mounjaro in Fayetteville NC
Semaglutide vs Ozempic vs Wegovy vs Mounjaro in Fayetteville NC

Table of Contents:

What is the difference between Semaglutide, Ozempic, Wegovy, and Mounjaro?
What are Semaglutide, Mounjaro, Wegovy, and Ozempic approved for?
Which one do we choose?
Do these medications keep weight off long term?

Semaglutide and tirzepatide are both GLP1 receptor agonists, but tirzepatide is also a GIP receptor agonist. They are both used to treat diabetes as well as obesity.

What is the difference between Semaglutide, Ozempic, Wegovy, and Mounjaro?


While Semaglutide, Ozempic, Wegovy, and Mounjaro all belong to the class of GLP-1 receptor agonists, there are crucial distinctions between them. Semaglutide (sold under the brand name Ozempic for diabetes and Wegovy for weight management) is a once-weekly injectable medication. It has demonstrated significant efficacy in controlling blood glucose levels and contributing to weight loss. Tirzepatide (sold under the brand name Mounjaro for diabetes and Zepbound for weight management), is one of the newer additions to this medication class. Although its exact differences are still being studied, preliminary research suggests potential advantages in terms of dosing schedule and side effect profile. As always, it’s crucial to consult a healthcare professional to understand which medication may be the most suitable, considering individual health conditions and lifestyle.

What are Semaglutide, Mounjaro, Wegovy, and Ozempic approved for?


Semaglutide, Mounjaro, Wegovy, and Ozempic are all approved by the FDA for different uses. Semaglutide, marketed as Ozempic, is approved for the treatment of type 2 diabetes and as an adjunct to diet and exercise to improve glycemic control in adults. In its form as Wegovy, Semaglutide is approved for chronic weight management in adults with obesity or overweight who have at least one weight-related condition, again in conjunction with dietary changes and physical activity. Mounjaro, one of the newer GLP-1 receptor agonists, is still undergoing rigorous study and its exact approved uses are yet to be finalized. As with all medications, these treatments should be used under the guidance of a healthcare professional, and their efficacy and safety should be regularly reviewed.

Which one do we choose?


Your obesity medicine physician will evaluate your medical history and check labs to determine if you meet criteria for diabetes to determine which medication to start with. Also, certain medications are preferred based on your insurance coverage and sometimes we need to start with other medications before your insurance will cover these. We are well versed with knowing how to choose the medication that is best for you and the one that your insurance is most likely to cover.

Do these medications keep weight off long term?


Semaglutide, Mounjaro, Wegovy, and Ozempic all have potential for long-term weight management. However, their effectiveness can vary among individuals and often depends on adherence to a comprehensive treatment plan, including a balanced diet and regular exercise. Some studies have suggested that Semaglutide (Ozempic and Wegovy) and Mounjaro can significantly help keep weight off over the long term. However, it’s important to remember that these are adjunct treatments and should be used alongside lifestyle modifications. To fully understand the potential long-term benefits and how these medications may fit into your personalized health strategy, we recommend reaching out to the healthcare professionals at Cape Fear Physical Medicine in Fayetteville, NC. You can call us or book an appointment online for a thorough consultation. We serve patients from Fayetteville NC, Hope Mills NC, Cedar Creek NC, Eastover NC, Woodfield NC, and Fenix NC.